康百事的服務內容

NGS 客製化分析服務
自動化分析流程建置
資料庫管理系統建置
分析應用平台建置
針對您的實驗設計提出適當的解決方案

Functional genomics

  • De novo Assembly
  • Functional gene annotation

Genome variant analysis

  • SNPs and InDELs calling
  • Structural Variant calling

Population Genomics

  • GBS analysis
  • Association studies and GWAS

Selective Sequencing

  • Sequence capture analysis
  • Exome analysis
  • Gene panel analysis

Resequencing

  • Reference Guided Assembly
  • Genome reconstruction
  • Marker development
針對您的實驗設計提出適當的解決方案

Pure transcriptomics

  • De novo transcriptome assembly
  • Reference guided transcriptome assembly
  • Gene expression network analysis

RNA-Seq

  • Differential expression gene analysis
  • Identification of alternative splicing
  • Identification of gene fusions and chimeric transcripts

Functional analysis

  • Protein-Protein interaction
  • Gene ontologies
  • Pathway analysis
  • Gene set enrichment analysis

Custom analysis

  • Variant detection
  • smallRNA sequencing
  • lncRNA sequencing
針對您的實驗設計提出適當的解決方案

ChIP-seq analysis

  • Peak detection
  • Differential peak calling
  • Motif discovery

BS-seq analysis

  • Differentially methylated region detection
  • Discovery and annotation of promoters
針對您的實驗設計提出適當的解決方案

16s rRNA Amplicon Sequencing

  • Quantitative characterization of microbial diversity
  • Association of species/OTU and host phenotype or other environmental factors
  • Taxonomical classification
  • Integration of taxonomical and functional data
  • Functional classification
  1. Connectivity Map 藥物基因表達比對分析

    文獻:J Lamb et al. The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease. Science. 2006.

自動化分析流程建置

協助您大幅節省人力,提高整體產能、效率,降低人力配置門檻

參考案例
  1. 微生物多樣性分析自動化分析流程建置


    文獻:JG Caporaso et al. QIIME allows analysis of high- throughput community sequencing data. Nature Methods. Nature Methods. 2010

資料庫管理系統建置

針對您內部數據或是外面公開資料庫進行整合,提供數據查詢介面與數據分析

參考案例
  1. 穿戴式裝置之資料庫雲端整合以及數據分析

分析應用平台建置

為您建置符合您需求之分析應用平台

參考案例
  1. 客製化專屬分析平台搭建 - Galaxy


    文獻:J Goecks et al. Galaxy: a comprehensive approach for supporting accessble, reproducible, and transparent computational research in the life sciences. Genome Biology. 2010.

  2. Web Application - compassGWAS

    文獻:S Purcell et al. PLINK: A Tool Set for Whole-Genome Association and Popula- tion-Based Linkage Analyses. The American Journal of Human Genetics. 2007.

  3. Web Application - GeneEcho

    文獻:A Conesa et al. A survey of best practices for RNA-seq data analysis. Genome Biology. 2016.